Molecular control of anhydrobiosis



Genomics of hereditary cancers


FANTOM Muscles

Gene regulatory network in mammalian muscles (FANTOM Muscles initiative)


Genomic tools

Advanced genomic tools for biomedical studies

  • PhD thesis defended by Olga Kozlova
  • The defense of the dissertation of the PhD of biological sciences Olga Sergeevna Kozlova was held on March 26, 2019 in Moscow at the Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences (IMBB). The topic of the thesis: “Full-genome analysis of the heat shock protein system in extremophilic chironomics of the Chironomidae […]

  • Heat shock system helps bug come back to life after drying up
  • The larva of the sleeping chironomid, Polypedilum vanderplanki—a mosquito-like insect that inhabits semi-arid areas of Africa—is well known for being able to come back to life after being nearly completely desiccated, losing up to 97 percent of its body’s water content. However, the genetic mechanisms the insects use to achieve this feat, and, especially is the […]

Laboratory of Extreme Bio Lab

We are an international laboratory supported by Institute of Fundamental Medicine and Biology of Kazan Federal University (Russia) and RIKEN (Japan). We are focused on application of genomics and other omics technologies for uncovery of unique adaptations of living organism to extreme environments (including spaceflight) and developing of new technologies based on these mechanisms. Our special interest are ametabolic water-free (anhydrobiosis) and hypometabolic (torpor and hibernation) states in animals and the molecular mechanism behind. We develope new techniques for dry preservation of living cells for biomedical and agricultural needs. We also study genome-wide patterns of activity of cis-regulatory elements using advanced transcriptomics techniques in model and non-model organisms. In the field of translational medicine we are interested in hereditary genomics component in major types of cancers. In cooperation with leading medical institutions in Russia and Japan we develop country-wide database for pathogenic germline cancer mutations and link it to the medical needs.



Our international projects

MidgeBase 1.0 & ZENBU chicken